After discharge, which statement most accurately describes medication adherence?

• A. Continue taking immunosuppressants every day as directed
• B. Stop immunosuppressants when feeling well
• C. Take medications only when experiencing symptoms
• D. Self-adjust dosing without medical guidance

Answer: (A)

Sticking to daily immunosuppressants as prescribed is essential after discharge because these medications must be taken consistently to keep the immune system suppressed enough to protect a transplanted kidney. They have narrow therapeutic ranges, so maintaining steady drug levels helps prevent rejection and reduces the risk of infection or drug toxicity. Feeling well or having no symptoms does not mean it’s safe to stop or change the dose; rejection can occur even without noticeable warning signs. Adjusting dosing on your own without medical guidance is unsafe and can lead to under- or over-immunosuppression. To support adherence, use reminders, keep a labeled pillbox, and discuss any missed doses with your healthcare provider.