CKD progression typically leads to what outcome?

• A. Rapid remission
• B. Progressive loss of kidney function often requiring renal replacement therapy
• C. Immediate cure with diet
• D. Kidney function remains stable

Answer: (B)

Chronic kidney disease is a long-term, progressive loss of kidney function. As it progresses, the glomerular filtration rate declines and waste products, fluids, and electrolytes build up, leading to worsening symptoms and complications. The typical course is a continued deterioration of kidney function that eventually reaches end-stage kidney disease, at which point renal replacement therapy—such as dialysis or a kidney transplant—is usually required to sustain life. While management can slow progression and improve quality of life, CKD is not generally cured or stabilized in the long term. Rapid remission or an immediate cure with diet is not characteristic of CKD, making the progression to renal replacement therapy the most likely outcome.