In the scenario of possible organ rejection, which instruction should the nurse give the client?

• A. Advise the client to come to the clinic right away for further evaluation.
• B. Wait until the next scheduled appointment.
• C. Start NSAIDs at home.
• D. Ignore symptoms.

Answer: (A)

Recognizing and acting quickly on possible organ rejection is essential because the graft can be harmed rapidly if rejection is not treated. The best instruction is to come to the clinic right away for evaluation. Early assessment lets the transplant team check graft function, order labs to assess organ performance, look for signs of immune attack, and decide whether to adjust immunosuppressive therapy or pursue a biopsy if needed. Prompt care can prevent irreversible damage and improve the chances of saving the graft.

Be aware of symptoms that should trigger urgent evaluation, such as new or worsening fever, tenderness, swelling or warmth at the transplant site, weight gain from fluid buildup, reduced urine output (for kidney transplants), high blood pressure, or general malaise. The workup may include blood tests, imaging, and possibly a biopsy to confirm rejection and guide treatment. Avoid NSAIDs at home because they can harm kidney function and interact with transplant medications. Ignoring symptoms or waiting for the next routine appointment can allow rejection to progress and jeopardize the transplant, so seek care promptly, including urgent care or the emergency department if symptoms are severe or rapidly worsening.