Which statement about immunosuppressants is true?

• A. They cure immune disorders
• B. They reverse organ rejection
• C. They prevent organ rejection by suppressing the immune response
• D. They have no role in transplant care

Answer: (C)

The main idea is that immunosuppressants prevent organ rejection by dampening the immune response. After a transplant, the recipient’s immune system may see the donor organ as foreign and attack it. Immunosuppressants curb that attack by reducing T-cell activation and proliferation, lowering the chances of rejection and helping the graft survive. They don’t cure immune disorders, nor do they automatically reverse established rejection on their own; their primary role is to prevent rejection and maintain graft function. These drugs are essential in transplant care and are typically used in combination to balance preventing rejection with the risk of infection and other side effects. Side effects can include higher infection risk, nephrotoxicity with some agents, and metabolic changes, so ongoing monitoring of drug levels and organ function is important.